OPC UA distinguishes between light-weight Variables called Properties and DataVariables (see OPC 10000-3).
Properties are expected to describe the Node they belong to and have several special rules (see OPC 10000-3). They are always of VariableType PropertyType (which is not allowed to be subtyped) and referenced with a HasProperty Reference. The BrowseName defines the sematic. They are the leaf of any hierarchy, meaning they cannot be the source of any hierarchical Reference and therefore not have any Properties by themselves.
Property values typically don’t change very often, and are usually read once and not subscribed to for changes.
DataVariables are of VariableType BaseDataVariableType or any subtype and do not have the restrictions of the Properties.
The decision to use a Property or DataVariable can to a certain degree be made on a semantic level. If the value describes the Node (like the engineering unit of a Variable), it is a Property; if it is something from the real world (like a measured temperature), it is a DataVariable. However, making the decision based on the semantic is not always that clear.
There are also the functional differences between Property and DataVariable. If your Variable needs Properties (like the engineering unit), you have to use a DataVariable, even if the semantic suggests that it should be defined as a Property.
As Properties have limited functionality, the recommendation is to use Properties when it is clear from the semantic that it is just describing the characteristics of the Node and there is no need to add additional information to the Variable, also not as extensible mechanism in vendor-models or other Companion Specifications. Otherwise, it is recommended to use DataVariables.